2025年のIMAT試験では、当校の模擬試験と同じ形式の問題が複数出題されました。

類似していた問題の詳細に関しては、当校のこちらのページにて公開しておりますので、

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生物

2025年 IMAT 13「生体エネルギー学 ― 酸化的リン酸化」

13. Oxidative phosphorylation is a metabolic pathway:
A) through which the energy stored in reduced coenzymes is used for the synthesis of ATP
B) through which the amino group resulting from the degradation of amino acids is eliminated
C) through which fatty acids are broken down by removing two carbon atoms at a time
D) which represents the final stage of the anabolism of amino acids, carbohydrates, and fatty acids
E) through which fatty acid synthesis occurs

正答 A

2025年度 第1回 IMAT模擬試験 10

10. Which process is primarily responsible for the production of ATP in the mitochondria?

A) Oxidative phosphorylation
B) Glycolysis
C) Light-dependent reactions
D) Anaerobic fermentation
E) Protein synthesis

正答 A

両方ともATPをつくる主要な仕組みとしての「酸化的リン酸化」を問う問題です。
ミトコンドリアでのATP生成の中心経路を理解しているかを確認しています。

2025年 IMAT 16「生理学 ― 筋肉」

16. Muscle contraction is triggered by an increase in the concentration of calcium ions that bind to:
A) troponin
B) myosin
C) tropomyosin
D) actin
E) vimentin

正答 A

2025年度 第4回 IMAT模擬試験 21

21. During skeletal muscle contraction, which event directly exposes the myosin-binding sites on actin filaments?

A) ATP hydrolysis by myosin heads
B) Release of calcium ions from the sarcoplasmic reticulum
C) Binding of calcium to troponin
D) Sliding of actin filaments past myosin filaments
E) Depolarization of the sarcolemma

正答 C

両方とも筋収縮を始める仕組みとして、カルシウムがトロポニンに結合する点を問う問題です。
筋収縮が始まる直接の仕組みを理解しているかを確認しています。。

2025年 IMAT 19「有機分子 ― 酵素」

19 Which of the following compounds corresponds to the statement “a substance that increases the speed of a reaction and is found unchanged at the end of it”?

A) Catalyst
B) Effector
C) Cofactor
D) Modulator
E) Cholesterol

正答 A

2025年8月実施 内部生向け模擬試験③

10 Which of the following best defines an enzyme?

A) A lipid molecule that stores energy.
B) A nucleic acid that encodes genetic information.
C) A protein that acts as a biological catalyst by lowering activation energy.
D) A carbohydrate that provides structural support to plant cells.
E) A vitamin required only as a cofactor in digestion.

正答 C

両方とも「触媒作用」をキーワードに、酵素の本質を問う問題です。
酵素が反応を速め、反応後も変化しない性質を理解しているかを確認しています。

2025年 IMAT 25「生体エネルギー学／代謝 ― 尿素回路」

25 Which of the following metabolic processes occurs mainly in the liver?

A) Urea cycle
B) Glycolysis
C) β-oxidation of fatty acids
D) The Krebs Cycle
E) Transamination

正答 A

2025年8月実施 内部生向け模擬試験②

32. Which of the following correctly describes a function of the human liver?

A) Secretion of digestive enzymes directly into the duodenum
B) Storage of bile within the liver for release during digestion
C) Conversion of ammonia (NH3) into urea for excretion
D) Production of insulin and glucagon for blood glucose regulation
E) Destruction of aged red blood cells as the primary site of hemolysis

正答 C

両方とも肝臓特有の役割として「尿素合成（アンモニアの処理）」を取り上げています。
窒素代謝における肝臓の重要性を確認する問題です。

2025年 IMAT 29「細胞生物学 ― 細胞膜」

29 What is the main function of the plasma membrane in cells?

A) Regulating exchanges between the inside and outside of the cell
B) Providing energy to the cell
C) Synthesizing proteins
D) Containing the cell’s genetic material
E) Facilitating cell movement

正答 A

2025年度 第2回 IMAT模擬試験 15

15 The fluid mosaic model describes the structure of the plasma membrane, which consists of a phospholipid bilayer with embedded proteins. Some of these proteins function as transporters, allowing specific molecules to enter or exit the cell.

Others act as receptors, facilitating cell signaling. The fluid nature of the membrane is crucial for cell function, enabling endocytosis, cell movement, and interaction with the environment. Which of the following observations would provide the strongest evidence supporting the fluid mosaic model of the plasma membrane?

A) Cells can selectively absorb and expel substances through active transport mechanisms.
B) Membrane proteins and lipids are able to diffuse laterally within the bilayer.
C) The plasma membrane contains carbohydrates attached to lipids and proteins.
D) The membrane is impermeable to large, charged molecules without protein assistance.
E) The phospholipid bilayer forms a continuous barrier that maintains cell integrity.

正答 B

両方とも細胞膜の役割と「流動モザイクモデル」に注目しています。物質輸送や膜タンパク質の動きについての理解を確認しています。

化学

2025年 IMAT 34「酸化還元」

34 In which of these compounds does Cl have an oxidation number of +3:

A) HClO2
B) Cl2
C) HCl
D) HClO
E) HClO3

正答 A

2025年8月実施 内部生向け模擬試験①

43 Which of the following compounds or species contains chlorine in the lowest oxidation state?

A) Cl₂
B) HCl
C) ClO⁻
D) ClO₃⁻
E) ClO₄⁻

正答 B
両方とも塩素の酸化数を見抜くことをテーマにしています。
化合物ごとの酸化状態を判定する力を問う問題です。

2025年 IMAT 36「原子・分子構造」

36. What kind of solid is NaCl?

A) Ionic
B) Molecular
C) Metallic
D) Covalent network
E) Amorphous

正答 A

2025年8月実施 内部生向け模擬試験③

33 A student dissolves NaCl and sucrose (C₁₂H₂₂O₁₁) separately in water. She observes that the NaCl solution conducts electricity, but the sucrose solution does not. Which of the following best explains this observation?

A) NaCl has a lower melting point than sucrose.
B) NaCl forms covalent bonds that allow for conductivity.
C) NaCl dissociates into ions; sucrose does not.
D) Sucrose reacts with water to form a gas.
E) Both substances conduct equally, but the student made a mistake.

正答 C

両方ともNaClの性質に関連し、イオン性物質としての特徴を扱っています。
結合の種類や水溶液での電気伝導性を理解しているかを確認する問題です。

2025年 IMAT 37「周期表」

37. In the periodic table, the atomic radius increases going:

A) from right to left and from top to bottom
B) from left to right and from top to bottom
C) from right to left and from bottom to top
D) from left to right and from bottom to top
E) from top to bottom but horizontally in a very irregularly way

正答 A

2025年度 第4回 IMAT模擬試験 38

38 Which ion has the largest radius among the following?

A) O²⁻
B) Mg²⁺
C) Al³⁺
D) Na⁺
E) F⁻

正答 A

両方とも原子やイオンの大きさに関する周期表の傾向を問っています。
周期律に基づく大きさの変化を理解しているかを確認する問題です。

2025年 IMAT 39「酸塩基（ph）」

39. The pH of an aqueous solution of a monoprotic weak acid with the constant Ka = 1.0 × 10⁻⁵ and concentration 0.001 M is:

A) 4
B) 3
C) 10⁻⁸
D) 8
E) 5.5

正答 A

2025年度 第2回 IMAT模擬試験 42

42. What volume (mL) of 0.200 mol/L NaOH is needed to completely neutralize 50.0 mL of 0.100 mol/L H₂SO₄?

A) 12.5
B) 25.0
C) 50.0
D) 75.0
E) 100.0

正答 C

両方とも酸と塩基の量的関係を扱っています。
pH計算と中和計算という形で酸塩基反応の理解を確認しています。

2025年 IMAT 41「化学平衡」

41. Given the equilibrium Heat + 2FeCl₃ (s) ⇌ 2FeCl₂ (s) + Cl₂ (g)
Which of the following options is correct:

A) to shift the equilibrium to the left, it is necessary to increase the concentration of Cl₂.
B) to shift the equilibrium to the left, it is necessary to increase the concentration of FeCl₂ (s).
C) to shift the equilibrium to the left, it is necessary to remove FeCl₃ (s).
D) to shift the equilibrium to the right, it is necessary to cool the reaction.
E) to shift the equilibrium to the right, it is necessary to increase the concentration of FeCl₃ (s).

正答 A

2025年度 第3回 IMAT模擬試験 40

40. N₂O₄(g) ⇌ 2NO₂(g), ΔH = +58 kJ·mol⁻¹

Which of the following changes would increase the yield of NO₂?

Increasing the temperature

Increasing the pressure

Removing NO₂ as it forms

Adding an inert gas at constant pressure

A) 1 and 3 only

B) 1 and 2 only

C) 2 and 3 only

D) 3 and 4 only

E) 1, 3 and 4 only

正答 E

両方とも化学平衡が条件の変化でどう動くかを扱っています。
ルシャトリエの原理を応用できるかを確認する問題です。

2025年 IMAT 42「反応エネルギー」

42. The activation energy of a reaction represents:

A) the energy barrier that the reactants must overcome to transform into products
B) the difference between the energy of the products and that of the reactants
C) the difference between the kinetic energy and the potential energy of the reactants
D) the energy released during the progress of a reaction
E) the energy that is released only in the initial phase of any reaction in solution

正答 A

2025年8月実施 内部生向け模擬試験②

46.What is activation energy?

A) The energy released when a bond is formed
B) The minimum energy required to start a chemical reaction
C) The total energy of the products
D) The difference between Gibbs free energy and entropy
E) The energy absorbed in an endothermic reaction

正答 B

両方とも「活性化エネルギー」の意味を問う問題です。
反応が始まるために必要なエネルギー障壁の理解を確認しています。

物理

2025年 IMAT 59「運動方程式」

59. A car with a mass of 2.0 × 10³ kg travels in a straight line at a constant speed on a flat road. Its speed is 15 m/s. At a certain moment (t = 0) it accelerates with a constant acceleration of 2.0 m/s², in the same direction as the velocity. The constant friction force is 2000 N. The forces F₁ and F₂ exerted by the engine in the first and second segments, respectively, are:

A) F₁ = 2000 N, F₂ = 6000 N
B) F₁ = 0, F₂ = 4000 N
C) F₁ = 0, F₂ = 6000 N
D) F₁ = 30 × 10³ N, F₂ = 4000 N
E) F₁ = F₂ = 2000 N

正答 A

2025年度 第2回 IMAT模擬試験 60

60. A car of mass 1,200 kg is moving at a speed of 20 m/s when the driver

suddenly applies the brakes. The car comes to a complete stop in 4 seconds.

Assuming the braking force is constant, what is the magnitude of the force

applied by the brakes?

A) 3,000 N
B) 6,000 N
C) 9,600 N
D) 12,000 N
E) 15,000 N

正答 B

両方とも「運動方程式」の意味を問う問題です。
力と加速度の関係を理解し、それを与えられた状況に基づいて、計算に用いることができるかを確認しています。

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